We’re happy to reconnect with you following the recent government shutdown. We hope that everyone enjoyed a pleasant, and perhaps relaxing, Thanksgiving holiday. As the year winds down, we wish you all a joyful and restful holiday season.
Thank you to everyone who submitted proposals in response to the recent funding opportunities (RFA-AR-25-013 and RFA-AR-25-014). The submission period has now closed, and we look forward to learning about the outcomes in the coming months.
NIH Standardized Organoid Modeling Center
New Approach Methodologies (NAMs) are becoming an important area of focus for the NIH. Recently, NIH introduced the Standardized Organoid Modeling (SOM) Center, which provides valuable resources and information to the research community. We encourage investigators and study teams to review the materials available at nih.gov/som in preparation for upcoming discussions and opportunities related to stem cell and cell therapies.
Catalog of Cell Type Molecular Markers
The Regenerative Medicine Innovation Program (RMIP) has generated extensive single cell transcriptomic data, a valuable resource for identifying cell types within complex samples. This process depends on reliable molecular markers and gene signatures to distinguish subtypes.
We invite consortia members to participate in creating a community-generated catalog of these markers that can be used to identify cell types. A page has been created on the BDC community forum for investigators to share markers you use to identify specific cell types, and join discussions to generate gene sets and develop confidence metrics for cell type identification. By working together, we can establish a trusted, widely used reference to advance regenerative medicine research.
Publications
Congratulations to the following study teams for their recent publications or preprints:
Silver SE, Mei Y, et al., Hypoimmunogenic hPSC-derived cardiac organoids for immune evasion and heart repair. bioRxiv [Preprint] 2025. doi: 10.1101/2025.04.09.648007
If you have recently submitted or published a manuscript related to your RMIP award, please submit the citation to jstratford@rti.org.
Meet with Us
BDC now has office hours each Wednesday from 2:00 to 3:00 PM ET to assist investigators with aggregating and harmonizing RMIP study data on the ecosystem.
We continue to coordinate one-on-one meetings with study teams to discuss a data linkage strategy. This strategy will ensure that the cell characterization data is prepared and formatted appropriately for seamless sharing with the study team. The goal is to facilitate efficient data transfer and analysis.
Jeran Stratford
December 2025 RMIP Updates
We’re happy to reconnect with you following the recent government shutdown. We hope that everyone enjoyed a pleasant, and perhaps relaxing, Thanksgiving holiday. As the year winds down, we wish you all a joyful and restful holiday season.
Thank you to everyone who submitted proposals in response to the recent funding opportunities (RFA-AR-25-013 and RFA-AR-25-014). The submission period has now closed, and we look forward to learning about the outcomes in the coming months.
NIH Standardized Organoid Modeling Center
New Approach Methodologies (NAMs) are becoming an important area of focus for the NIH. Recently, NIH introduced the Standardized Organoid Modeling (SOM) Center, which provides valuable resources and information to the research community. We encourage investigators and study teams to review the materials available at nih.gov/som in preparation for upcoming discussions and opportunities related to stem cell and cell therapies.
Catalog of Cell Type Molecular Markers
The Regenerative Medicine Innovation Program (RMIP) has generated extensive single cell transcriptomic data, a valuable resource for identifying cell types within complex samples. This process depends on reliable molecular markers and gene signatures to distinguish subtypes.
We invite consortia members to participate in creating a community-generated catalog of these markers that can be used to identify cell types. A page has been created on the BDC community forum for investigators to share markers you use to identify specific cell types, and join discussions to generate gene sets and develop confidence metrics for cell type identification. By working together, we can establish a trusted, widely used reference to advance regenerative medicine research.
Publications
Congratulations to the following study teams for their recent publications or preprints:
If you have recently submitted or published a manuscript related to your RMIP award, please submit the citation to jstratford@rti.org.
Meet with Us
BDC now has office hours each Wednesday from 2:00 to 3:00 PM ET to assist investigators with aggregating and harmonizing RMIP study data on the ecosystem.
We continue to coordinate one-on-one meetings with study teams to discuss a data linkage strategy. This strategy will ensure that the cell characterization data is prepared and formatted appropriately for seamless sharing with the study team. The goal is to facilitate efficient data transfer and analysis.
Resources, Materials and Support
Slides and Video from RMIP Orientation
FAQs from the Orientation Sessions
BDC Resource Hub
Join the Community for full interaction with our support services
RMIP BDC Office Hours Wednesday 2:00-3:00PM ET
Velsera Seven Bridges Office Hours at on Tuesdays at 10:00-11:00 AM ET and Thursdays at 2:00-3:00 PM ET
BDC Powered by Seven Bridges Onboarding videos*
Submit suggestions for future short-form videos
Submit a question or raise a ticket with our Help Desk
Navigating BDC YouTube Channel
If you use BDC in your work, don’t forget to cite us.
BDC Documentation or the Seven Bridges Knowledge Center