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GWAS with Multinomial Regression

Hello BDC Community, 


A researcher, Katie Chan, has a need for a GWAS package that can perform multinomial regression.

Background:
Katie was originally interested in the software Trinculo, which is an open source C compiled program, but that software appears to have been abandoned, and we (BDC-Seven Bridges) are wary of telling her to use something that the developer doesn't support. The other option we've found is a Julia-based package for the OpenMendel project with several more recent publications (Ordered multinomial regression for genetic association analysis of ordinal phenotypes at Biobank scale. (escholarship.org)). This might work, but would take development to implement.

Questions for the Community
1) For Katie, immediately, does anyone have a good suggestion for software or scripts that are ready to go, and can do ordinal multinomial regression? 

2) Is there interest in the rest of the community for something that can do multinomial regression? (If so, does anyone have a recommendation other than this Julia package?) 

Katie: Would you be willing to explain a little bit more about what you're trying to do? What phenotypes are you looking at, and how did you determine that you wanted to do multinomial regression instead of looking at one phenotype at a time?  

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